Categoría: Oncology & Cancer
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Tracking mysteries of loss of Y chromosome, cancer
The Y chromosome is among the smallest in the human body and carries the fewest genes. Researchers are paying renewed attention to its role in cancer—specifically, what happens when it vanishes.
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What is a ‘cancer gene’? How genetic mutations lead to cancer
An estimated 170,000 Australians were diagnosed with cancer in 2025. Many people know the causes of cancer are partly genetic. But how do your genes, which contribute so much of what makes you you, change what they do and cause a cancer?
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Jumping ‘DNA parasites’ linked to early stages of tumor formation
A study published in the journal Science reveals how jumping fragments of human DNA, a type of genetic parasite, destabilize the cancer genome. Unstable genomes are a fertile playground for cancer evolution, giving malignant cells more opportunities to…
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‘Off the shelf’ immunotherapy could get a lift from gene-edited natural killer cells
Since scientists first discovered that human immune cells could be modified to become cancer-fighting agents, they’ve been trying to engineer a cell that’s effective against solid tumors, which account for the vast majority of cancer cases. In a key ad…
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Researchers drill down on genetic profiles to guide treatment for leukemia patients
Cancer researchers are making strides in efforts to use genetic profiling to develop a more precise understanding of the response to treatment of acute myeloid leukemia (AML), a rare but aggressive blood cancer.
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Household cat could hold the key to understanding breast cancer
The first study of multiple cancer types in cats has identified genetic changes that could help treat the condition in humans and animals. By analyzing different types of tumors from almost 500 pet cats across five countries, experts at the Wellcome Sa…
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Urine DNA test may spot Lynch syndrome urinary cancers before symptoms
A pioneering genetic test is improving early diagnosis and treatment for people with hereditary cancer caused by a genetic condition. The test, developed with the help of Newcastle University scientists, identifies specific signs in a person’s DNA that…
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KRAS mutation type may guide more effective cancer treatments
KRAS is the most frequently mutated oncogene across all human cancers. Although different KRAS mutations have long been thought to exert the same cancer-driving effects, a new study led by UT Southwestern Medical Center researchers suggests that differ…
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Genetic risk may rival obesity as a key driver of endometrial cancer
A major new study has found genetics play a powerful and independent role in endometrial cancer risk—challenging the long-held belief that obesity is the primary driver. The findings could lead to better screening of the women most at risk of developin…
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Discovery of unique brain tumor subtypes offers hope for targeted glioma therapies
Researchers have uncovered the mechanisms behind three unique subtypes of mismatch repair deficient high-grade gliomas. The findings provide a clearer understanding of how these tumors develop, explain why patients respond differently to immunotherapy,…
