Categoría: Oncology & Cancer

Case Western Reserve University researchers have made a significant breakthrough in understanding Barrett’s esophagus, a precancerous condition that dramatically increases the risk of developing esophageal adenocarcinoma, one of the fastest-spreading a…

A genetic test developed by researchers at Broad Clinical Labs and the U.S. Department of Veterans Affairs (VA) is now enabling a large, nationwide clinical trial aimed at improving health care for men at increased risk of developing prostate cancer, t…

Cells from cancerous tumors can spread, or metastasize, throughout the body. Researchers have long sought to understand what determines where those cells will go and thrive in order to more effectively treat the cancer and prevent metastasis. Researche…

DNA’s iconic double helix does more than «just» store genetic information. Under certain conditions, it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown that one such structure, known as i-DNA, not only f…

Researchers from the HUN-REN Szeged Biological Research Centre and HCEMM have just published a new study suggesting that it’s not simply the number of tumor mutations that matters for immunotherapy, but the kind of mutation patterns they create. The te…

Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumor growth. The study focused on CTNNB1, a gene that produces the protein β-catenin, which helps regulate tissue growth and repair. When …

Genetic ancestry plays a key role in determining the behavior of head and neck tumors and may help explain why African-American patients survive for half as long as their counterparts of European ancestry, according to a new review study led by researc…

Researchers at LUMC have made a breakthrough in understanding PALB2 mutations, an important cause of hereditary breast cancer. By identifying which mutations affect the function of PALB2, doctors can now assess much more accurately which mutations are …

A paper published in Biology Methods and Protocols, indicates that a new computational method may help researchers identify effective precision treatments for cancer more quickly and efficiently. The paper is titled «SOLVE: A Structured Orthogonal Late…

Researchers from the Faculty of Engineering at The University of Hong Kong (HKU) have developed two innovative deep-learning algorithms, ClairS-TO and Clair3-RNA, that significantly advance genetic mutation detection in cancer diagnostics and RNA-based…