Categoría: Oncology & Cancer
-
Rb1 identified as predictive biomarker for new therapeutic strategy in some breast cancers
A new study published in Science Translational Medicine by researchers at The University of Texas MD Anderson Cancer Center details a therapeutic vulnerability in patients with an aggressive subtype of triple-negative breast cancer.
-
BRAF gene mutation leads to different therapeutic responses in melanoma and colorectal cancer
A review article led by researchers from the B·ARGO group at the Germans Trias i Pujol Research Institute (IGTP) and from the Medical Oncology Department of the Catalan Institute of Oncology (ICO) in Badalona provides a comparative analysis of the impa…
-
Genomic test helps flag early aggressive prostate cancer in African American patients
A new Moffitt Cancer Center study suggests a widely used genomic test can more accurately identify which men with early prostate cancer are at high risk for their disease to come back quickly after treatment, particularly African American men who face …
-
Scientists show targeting cancer stem cells can prevent gastric cancer recurrence
Scientists from A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB) have identified the specific cells responsible for gastric cancer’s tendency to return after treatment. The study also demonstrated that eliminating these cells stops tumors f…
-
Cancer’s hidden ‘safety switch’: Silencing TAK1 gene could boost immunotherapy performance
Australian researchers have discovered that the TAK1 gene helps cancer cells survive attack from the immune system, revealing a mechanism that may limit the effectiveness of immunotherapy treatments.
-
Subtyping colorectal cancer may improve patient outcome predictions
Colorectal cancer, or CRC, is the world’s second most lethal cancer based on the number of deaths, and is the third most prevalent malignant tumor. Doctors and patients have long been hoping for better diagnostics for prognosis, such as molecular subty…
-
‘Molecular glue’ stabilizes protein that inhibits development of non-small cell lung cancer
Lung cancer is the second-most common cancer and the leading cause of cancer death in the United States. Over 80% of lung cancers are non-small cell lung cancers, in which tumor cells are larger and grow more slowly than those in small cell lung cancer.
-
Multiple myeloma develops differently in men and women, study reveals
Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have uncovered biological differences in how multiple myeloma develops and progresses in men and in women. The rare blood cancer occurs more often in men than in wo…
-
Alcohol-linked DNA damage tied to cancer risk: Study reveals repair enzyme’s role
Alcohol consumption leads to the formation of a toxic compound called acetaldehyde, which damages DNA. A research team from IOCB Prague has now described in detail how cells repair this damaged genetic information.
-
Fertility gene helps glioblastoma tumors survive chemotherapy and return after treatment, researchers discover
Research by University of Sydney scientists has uncovered a mechanism that may explain why glioblastoma returns after treatment, offering new clues for future therapies which they will now investigate as part of an Australian industry collaboration.