Categoría: Oncology & Cancer
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Order of genetic mutations shapes cancer’s development and patient outcomes
In many aspects of our lives, we find meaning in the order in which events occur. We buy into myths about «middle child syndrome,» talk of calm before storms, and consider it strange to start a meal with dessert.
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Heat shock protein masks BRCA1 mutations, suggesting a new treatment path
Researchers from The University of Texas MD Anderson Cancer Center identified a new role for heat shock protein 90 (HSP90) in cancer predisposition and treatment resistance.
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Gene scissors in camouflage mode help in the search for cancer therapies
The immune system plays a crucial role in fighting tumors and metastases. Consequently, it is decisive to conduct cancer research in mouse models with an immune system that is as natural as possible—which is easier said than done.
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Chronic lymphocytic leukemia: New origins and biomarkers revealed
Researchers at the University of Eastern Finland and their international collaborators have identified key developmental and molecular differences between the two main subtypes of chronic lymphocytic leukemia, CLL. The findings, published in PLOS ONE, …
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RNA therapy silences KRAS gene and boosts immune attack on cancer cells
Two complementary studies led by researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have demonstrated a new RNA-based therapeutic strategy that effectively targets one of the most difficult-to-treat c…
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CRISPR breakthrough reverses chemotherapy resistance in lung cancer
In a major step forward for cancer care, researchers at ChristianaCare’s Gene Editing Institute have shown that disabling the NRF2 gene with CRISPR technology can reverse chemotherapy resistance in lung cancer. The approach restores drug sensitivity an…
