Categoría: MedicalXPress
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Scientists build virtual tissue tools to map how cells talk in disease
Scientists at Duke-NUS Medical School have developed two powerful computational tools that could transform how researchers study the «conversations» between cells inside the body. The tools, called sCCIgen and QuadST, help scientists understand both wh…
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Major gaps block genetic evaluation and testing for Black and low income patients, study finds
Black patients and patients from socioeconomically disadvantaged neighborhoods are dramatically under-represented in genetics clinics—often at rates half or less than those of white patients or individuals from wealthier areas—according to researchers …
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Homer1 gene calms the mind and improves attention in mice
Attention disorders such as ADHD involve a breakdown in our ability to separate signal from noise. The brain is constantly bombarded with information, and focus depends on its ability to filter out distractions and detect what matters.
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Improving diagnosis of aortic stenosis with genetics and AI
Aortic stenosis is a narrowing of the aortic valve, which connects the heart to the rest of the body. It affects millions of people and can be fatal if left untreated. At present, there are no effective medical therapies to prevent or slow its progress…
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Genomic test helps flag early aggressive prostate cancer in African American patients
A new Moffitt Cancer Center study suggests a widely used genomic test can more accurately identify which men with early prostate cancer are at high risk for their disease to come back quickly after treatment, particularly African American men who face …
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Scientists show targeting cancer stem cells can prevent gastric cancer recurrence
Scientists from A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB) have identified the specific cells responsible for gastric cancer’s tendency to return after treatment. The study also demonstrated that eliminating these cells stops tumors f…
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Cancer’s hidden ‘safety switch’: Silencing TAK1 gene could boost immunotherapy performance
Australian researchers have discovered that the TAK1 gene helps cancer cells survive attack from the immune system, revealing a mechanism that may limit the effectiveness of immunotherapy treatments.
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Subtyping colorectal cancer may improve patient outcome predictions
Colorectal cancer, or CRC, is the world’s second most lethal cancer based on the number of deaths, and is the third most prevalent malignant tumor. Doctors and patients have long been hoping for better diagnostics for prognosis, such as molecular subty…
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Hidden ‘switches’ in DNA reveal new insights into Alzheimer’s disease
A tiny percentage of our DNA—around 2%—contains 20,000-odd genes. The remaining 98%—long known as the non-coding genome, or so-called ‘junk’ DNA—includes many of the «switches» that control when and how strongly genes are expressed.
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Is aging an act of genetic sabotage? Scientists find a gene that turns off food detection after reproduction
When roundworms stop reproducing, they can still move and function normally but lose their ability to detect certain food odors that once led them to their meals.