Categoría: Genetics
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Improving diagnosis of aortic stenosis with genetics and AI
Aortic stenosis is a narrowing of the aortic valve, which connects the heart to the rest of the body. It affects millions of people and can be fatal if left untreated. At present, there are no effective medical therapies to prevent or slow its progress…
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Hidden ‘switches’ in DNA reveal new insights into Alzheimer’s disease
A tiny percentage of our DNA—around 2%—contains 20,000-odd genes. The remaining 98%—long known as the non-coding genome, or so-called ‘junk’ DNA—includes many of the «switches» that control when and how strongly genes are expressed.
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Is aging an act of genetic sabotage? Scientists find a gene that turns off food detection after reproduction
When roundworms stop reproducing, they can still move and function normally but lose their ability to detect certain food odors that once led them to their meals.
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Genetic influences on health can ripple through social groups via shared microbes
Your «roommate’s» genes could be influencing the bacteria living in your gut, and vice versa, according to a study of rats published in Nature Communications.
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Individual genetic differences can render some antibody-based therapies ineffective
Antibody-based therapies are used to treat numerous diseases, from cancer to rheumatic disorders and multiple sclerosis. Antibodies recognize and bind to very specific structures. This allows them to direct active substances to exactly the right target…
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How disabling one gene protects mice against Type 1 diabetes
Scientists at the University of Wisconsin–Madison have uncovered a possible way to protect key cells in the pancreas that are targeted during the development of Type 1 diabetes.
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Gene therapy advances as scientists guide jumping DNA to target faulty genes
JABSOM Cell and Molecular Biology researcher Dr. Jesse Owens has spent the better part of two decades chasing a vision that began with the revolutionary idea that DNA can move itself. Now, his team’s latest breakthrough is published in Nucleic Acids Re…
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New details on role of fat transport molecules in Alzheimer’s onset
A new study presents robust evidence on the role of lysophosphatidylcholines (LPCs) in the onset of Alzheimer’s disease. Researchers discovered that LPCs—compounds that transport a variety of healthy fatty acids to the brain—either promote Alzheimer’s …
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Childhood maltreatment leaves genetic scars tied to lifelong mental health risks
A research team led by the Department of Pediatrics and Adolescent Medicine, School of Clinical Medicine, LKS Faculty of Medicine, the University of Hong Kong (HKUMed), has conducted a pioneering study that established a causal link between childhood m…
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Using both genetic information and AI to diagnose pneumonia could curb the overuse of antibiotics
Lung infections like pneumonia are among the world’s top killers—but diagnosing them is notoriously hard. Now, researchers at UC San Francisco have found a way to identify these infections in critically ill patients by pairing a generative AI analysis …
