Autor: Genetics News – Genetics Science, Genetics Technology, Genetics
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Childhood maltreatment leaves genetic scars tied to lifelong mental health risks
A research team led by the Department of Pediatrics and Adolescent Medicine, School of Clinical Medicine, LKS Faculty of Medicine, the University of Hong Kong (HKUMed), has conducted a pioneering study that established a causal link between childhood m…
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Using both genetic information and AI to diagnose pneumonia could curb the overuse of antibiotics
Lung infections like pneumonia are among the world’s top killers—but diagnosing them is notoriously hard. Now, researchers at UC San Francisco have found a way to identify these infections in critically ill patients by pairing a generative AI analysis …
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Multiple myeloma develops differently in men and women, study reveals
Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have uncovered biological differences in how multiple myeloma develops and progresses in men and in women. The rare blood cancer occurs more often in men than in wo…
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Alcohol-linked DNA damage tied to cancer risk: Study reveals repair enzyme’s role
Alcohol consumption leads to the formation of a toxic compound called acetaldehyde, which damages DNA. A research team from IOCB Prague has now described in detail how cells repair this damaged genetic information.
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Study finds combined gene mutations better mimic rare gut disorder in mice
During development of the digestive system, a complex network of nerves forms around it, creating a «second brain»—the enteric nervous system (ENS)—which controls the movement of food and waste through the gut. But a combination of changes in the molec…
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Who is more likely to get long COVID? New study uncovers genetic drivers behind the disease
Australian scientists have identified the key genetic drivers behind long COVID, revealing why some people continue to experience debilitating symptoms long after their initial infection.
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Gene therapy for hereditary spastic paraplegia hits proof-of-principle milestone
There is no cure for the rare disease Hereditary Spastic Paraplegia (HSP), but researchers from Drexel University’s College of Medicine and the UMass Chan Medical School have achieved proof-of-principle success with «silence and replace» gene therapy—a…
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Refining the uncharted landscape of human transcription factors—strategic framework created for future prioritization
The human genome contains approximately 1,600 types of transcription factors responsible for regulating gene activity across more than 400 tissue and cell types. Chromatin immunoprecipitation sequencing (ChIP-seq) is a key approach for mapping how thes…
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Key proteins identified in Oroya fever reveal new target for potential treatment
The so-called «Oroya fever» is an extremely severe infectious disease, yet it is classified among the so-called neglected tropical diseases. This is because the infection occurs—so far—exclusively in high-altitude valleys of the South American Andes, p…
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Neurons use simple rules to localize genetic messages, scientists discover
Scientists found that messenger RNA (mRNA) molecules that carry genetic instructions to the far reaches of neurons in the brain tend to cluster together mostly because they are abundant, not because they move in coordinated groups.