{"id":92,"date":"2023-10-18T16:00:19","date_gmt":"2023-10-18T16:00:19","guid":{"rendered":"http:\/\/sebgc.es\/blog\/?guid=22fc8848a4f698b60134dfd1a122eafd"},"modified":"2023-10-18T16:00:19","modified_gmt":"2023-10-18T16:00:19","slug":"risk-perception-and-surveillance-uptake-in-individuals-at-increased-risk-for-pancreatic-ductal-adenocarcinoma","status":"publish","type":"post","link":"https:\/\/sebigec.es\/blog\/index.php\/2023\/10\/18\/risk-perception-and-surveillance-uptake-in-individuals-at-increased-risk-for-pancreatic-ductal-adenocarcinoma\/","title":{"rendered":"Risk perception and surveillance uptake in individuals at increased risk for pancreatic ductal adenocarcinoma"},"content":{"rendered":"<sec><st>Background<\/st><p>Surveillance for pancreatic ductal adenocarcinoma (PDAC) is recommended for high-risk individuals with genetic variants in PDAC-associated genes and\/or family history. Surveillance uptake and adherence may depend on the perception of PDAC risk and cancer worry. We aimed to determine PDAC risk perception in at-risk individuals and assess factors associated with PDAC surveillance uptake.<\/p><\/sec><sec><st>Methods<\/st><p>At-risk individuals identified from a prospective academic registry were sent a survey electronically. PDAC risk perception, cancer worry and surveillance uptake were surveyed. Factors associated with increased risk perception and surveillance were assessed. Five-year PDAC risk was calculated using the PancPRO risk assessment model, and correlation with subjective risk assessment was assessed.<\/p><\/sec><sec><st>Results<\/st><p>The overall survey response rate was 34% (279\/816). The median perceived PDAC risk was twofold (IQR 1&ndash;4) above respondents&rsquo; estimates of general population risk. Factors significantly associated with higher perceived PDAC risk included non-Hispanic white race, post-graduate education level, PDAC-affected first-degree relative, genetic variants and lack of personal cancer history. Cancer worry had a very weak correlation across PDAC risk estimates (r=0.16). No correlation between perceived PDAC risk and 5-year calculated PDAC risk was found. Older age, having a first-degree relative with PDAC, meeting with a medical provider about PDAC cancer risk and awareness of surveillance modalities were significant predictors of undergoing PDAC surveillance.<\/p><\/sec><sec><st>Conclusions<\/st><p>Individuals at risk for PDAC do not report risk perception that correlates with calculated risk. This presents an opportunity for counselling of at-risk patients to individualise management and improve surveillance uptake for eligible individuals.<\/p><\/sec>","protected":false},"excerpt":{"rendered":"<p>BackgroundSurveillance for pancreatic ductal adenocarcinoma (PDAC) is recommended for high-risk individuals with genetic variants in PDAC-associated genes and\/or family history. Surveillance uptake and adherence may depend on the perception of PDAC ris&#8230;<\/p>\n","protected":false},"author":11,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6,8],"tags":[],"class_list":["post-92","post","type-post","status-publish","format-standard","hentry","category-articulos","category-jmg-first"],"_links":{"self":[{"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/posts\/92","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/comments?post=92"}],"version-history":[{"count":1,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/posts\/92\/revisions"}],"predecessor-version":[{"id":93,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/posts\/92\/revisions\/93"}],"wp:attachment":[{"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/media?parent=92"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/categories?post=92"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/tags?post=92"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}