{"id":757,"date":"2023-12-14T01:00:00","date_gmt":"2023-12-14T01:00:00","guid":{"rendered":"http:\/\/sebgc.es\/blog\/?guid=02149cb1d1fe7bec8087ec6569344a4a"},"modified":"2023-12-14T16:00:00","modified_gmt":"2023-12-14T16:00:00","slug":"comparing-the-diagnostic-performance-of-quantitative-pcr-digital-droplet-pcr-and-next-generation-sequencing-liquid-biopsies-for-human-papillomavirus-associated-cancers","status":"publish","type":"post","link":"https:\/\/sebigec.es\/blog\/index.php\/2023\/12\/14\/comparing-the-diagnostic-performance-of-quantitative-pcr-digital-droplet-pcr-and-next-generation-sequencing-liquid-biopsies-for-human-papillomavirus-associated-cancers\/","title":{"rendered":"Comparing the Diagnostic Performance of Quantitative PCR, Digital Droplet PCR, and Next-Generation Sequencing Liquid Biopsies for Human\u00a0Papillomavirus\u2013Associated Cancers"},"content":{"rendered":"Human papillomavirus (HPV)-associated cancers, including oropharyngeal squamous cell carcinoma (HPV\u00a0+\u00a0OPSCC), cervical cancer, and squamous cell carcinoma of the anus (HPV\u00a0+\u00a0SCCA), release circulating tumor HPV DNA (ctHPVDNA) into the blood. The diagnostic performance of ctHPVDNA detection depends on the approaches used and the individual assay metrics. A comparison of these approaches has not been systematically performed to inform expected performance, which in turn affects clinical interpretation.","protected":false},"excerpt":{"rendered":"<p>Human papillomavirus (HPV)-associated cancers, including oropharyngeal squamous cell carcinoma (HPV\u00a0+\u00a0OPSCC), cervical cancer, and squamous cell carcinoma of the anus (HPV\u00a0+\u00a0SCCA), release circulating tumor HPV DNA (ctHPVDNA) into the blood. The diagno&#8230;<\/p>\n","protected":false},"author":150,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6,54],"tags":[55],"class_list":["post-757","post","type-post","status-publish","format-standard","hentry","category-articulos","category-the-journal-of-molecular-diagnostics","tag-jmoldiagn"],"_links":{"self":[{"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/posts\/757","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/users\/150"}],"replies":[{"embeddable":true,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/comments?post=757"}],"version-history":[{"count":2,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/posts\/757\/revisions"}],"predecessor-version":[{"id":838,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/posts\/757\/revisions\/838"}],"wp:attachment":[{"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/media?parent=757"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/categories?post=757"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/tags?post=757"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}