{"id":537,"date":"2024-01-02T19:00:00","date_gmt":"2024-01-02T19:00:00","guid":{"rendered":"http:\/\/sebgc.es\/blog\/?guid=1533124636f61a7b966ab8d6af651e17"},"modified":"2024-01-02T23:00:00","modified_gmt":"2024-01-02T23:00:00","slug":"a-bayesian-fine-mapping-model-using-a-continuous-global-local-shrinkage-prior-with-applications-in-prostate-cancer-analysis","status":"publish","type":"post","link":"https:\/\/sebigec.es\/blog\/index.php\/2024\/01\/02\/a-bayesian-fine-mapping-model-using-a-continuous-global-local-shrinkage-prior-with-applications-in-prostate-cancer-analysis\/","title":{"rendered":"A Bayesian fine-mapping model using a continuous global-local shrinkage prior with applications in prostate cancer analysis"},"content":{"rendered":"We develop a fine-mapping method, called h2-D2, utilizing a continuous global-local shrinkage prior, and propose an approach to define credible set of causal variants in this framework. Our proposed method outperforms the state-of-art fine-mapping methods based on discrete mixture priors.","protected":false},"excerpt":{"rendered":"<p>We develop a fine-mapping method, called h2-D2, utilizing a continuous global-local shrinkage prior, and propose an approach to define credible set of causal variants in this framework. Our proposed method outperforms the state-of-art fine-mapping meth&#8230;<\/p>\n","protected":false},"author":107,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6,41],"tags":[48],"class_list":["post-537","post","type-post","status-publish","format-standard","hentry","category-articulos","category-the-american-journal-of-human-genetics","tag-amjhumgenet"],"_links":{"self":[{"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/posts\/537","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/users\/107"}],"replies":[{"embeddable":true,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/comments?post=537"}],"version-history":[{"count":4,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/posts\/537\/revisions"}],"predecessor-version":[{"id":659,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/posts\/537\/revisions\/659"}],"wp:attachment":[{"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/media?parent=537"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/categories?post=537"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/tags?post=537"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}