{"id":525,"date":"2024-01-16T19:00:00","date_gmt":"2024-01-16T19:00:00","guid":{"rendered":"http:\/\/sebgc.es\/blog\/?guid=56722182c60474080313aaed63d70ef6"},"modified":"2024-01-16T23:00:00","modified_gmt":"2024-01-16T23:00:00","slug":"a-common-nfkb1-variant-detected-through-antibody-analysis-in-uk-biobank-predicts-risk-of-infection-and-allergy","status":"publish","type":"post","link":"https:\/\/sebigec.es\/blog\/index.php\/2024\/01\/16\/a-common-nfkb1-variant-detected-through-antibody-analysis-in-uk-biobank-predicts-risk-of-infection-and-allergy\/","title":{"rendered":"A common NFKB1 variant detected through antibody analysis in UK Biobank predicts risk of infection and allergy"},"content":{"rendered":"Infectious agents contribute significantly to the global burden of diseases, through both acute infection and their chronic sequelae. We identified an insertion-deletion variant thought to affect NFKB1 expression as a causal variant\u2014central to serological responses to diverse infectious agents, risk of infection, immune cell survival, antibody production, and inflammation.","protected":false},"excerpt":{"rendered":"<p>Infectious agents contribute significantly to the global burden of diseases, through both acute infection and their chronic sequelae. We identified an insertion-deletion variant thought to affect NFKB1 expression as a causal variant\u2014central to serologi&#8230;<\/p>\n","protected":false},"author":0,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6,41],"tags":[48],"class_list":["post-525","post","type-post","status-publish","format-standard","hentry","category-articulos","category-the-american-journal-of-human-genetics","tag-amjhumgenet"],"_links":{"self":[{"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/posts\/525","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/comments?post=525"}],"version-history":[{"count":4,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/posts\/525\/revisions"}],"predecessor-version":[{"id":653,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/posts\/525\/revisions\/653"}],"wp:attachment":[{"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/media?parent=525"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/categories?post=525"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/tags?post=525"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}