{"id":5195,"date":"2025-12-04T15:00:00","date_gmt":"2025-12-04T15:00:00","guid":{"rendered":"http:\/\/sebigec.es\/blog\/?guid=20f212372bc5f9e40288819bdfabc01d"},"modified":"2025-12-04T23:00:00","modified_gmt":"2025-12-04T23:00:00","slug":"alphagenome-a-swiss-army-knife-for-exploring-non-coding-dna","status":"publish","type":"post","link":"https:\/\/sebigec.es\/blog\/index.php\/2025\/12\/04\/alphagenome-a-swiss-army-knife-for-exploring-non-coding-dna\/","title":{"rendered":"AlphaGenome, a Swiss-army knife for exploring non-coding DNA"},"content":{"rendered":"AlphaGenome, recently announced in a preprint by Avsec et al., is Google DeepMind\u2019s powerful \u2018Swiss army knife\u2019 for predicting molecular effects from non-coding DNA. Remarkably, it does so with base-pair resolution while maintaining long-range context. Here, we discuss AlphaGenome\u2019s promise and limitations in prioritizing and functionally interpreting non-coding variants underlying human traits and diseases.","protected":false},"excerpt":{"rendered":"<p>AlphaGenome, recently announced in a preprint by Avsec et al., is Google DeepMind\u2019s powerful \u2018Swiss army knife\u2019 for predicting molecular effects from non-coding DNA. Remarkably, it does so with base-pair resolution while maintaining long-range context&#8230;.<\/p>\n","protected":false},"author":330,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6,65],"tags":[79],"class_list":["post-5195","post","type-post","status-publish","format-standard","hentry","category-articulos","category-trends-in-genetics","tag-trendsgen"],"_links":{"self":[{"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/posts\/5195","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/users\/330"}],"replies":[{"embeddable":true,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/comments?post=5195"}],"version-history":[{"count":24,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/posts\/5195\/revisions"}],"predecessor-version":[{"id":5387,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/posts\/5195\/revisions\/5387"}],"wp:attachment":[{"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/media?parent=5195"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/categories?post=5195"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/tags?post=5195"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}