{"id":14104,"date":"2026-03-19T17:00:00","date_gmt":"2026-03-19T17:00:00","guid":{"rendered":"http:\/\/sebigec.es\/blog\/?guid=cc2f9b213e7c62e4fa4bdcfa0c8e690c"},"modified":"2026-03-19T23:00:00","modified_gmt":"2026-03-19T23:00:00","slug":"best-practices-for-improving-alignment-and-variant-calling-on-human-sex-chromosomes","status":"publish","type":"post","link":"https:\/\/sebigec.es\/blog\/index.php\/2026\/03\/19\/best-practices-for-improving-alignment-and-variant-calling-on-human-sex-chromosomes\/","title":{"rendered":"Best practices for improving alignment and variant calling on human sex chromosomes"},"content":{"rendered":"Aligning and calling variants in a way that accounts for the sex chromosome complement of the sample will reduce false-positive variants and increase true-positive variants on the X and Y chromosomes.","protected":false},"excerpt":{"rendered":"<p>Aligning and calling variants in a way that accounts for the sex chromosome complement of the sample will reduce false-positive variants and increase true-positive variants on the X and Y chromosomes.<\/p>\n","protected":false},"author":525,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6,41],"tags":[48],"class_list":["post-14104","post","type-post","status-publish","format-standard","hentry","category-articulos","category-the-american-journal-of-human-genetics","tag-amjhumgenet"],"_links":{"self":[{"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/posts\/14104","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/users\/525"}],"replies":[{"embeddable":true,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/comments?post=14104"}],"version-history":[{"count":24,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/posts\/14104\/revisions"}],"predecessor-version":[{"id":14188,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/posts\/14104\/revisions\/14188"}],"wp:attachment":[{"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/media?parent=14104"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/categories?post=14104"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sebigec.es\/blog\/index.php\/wp-json\/wp\/v2\/tags?post=14104"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}