Categoría: Noticias
-
Mechanisms behind tumor suppressor BAP1 highlight new treatment strategies for aggressive cancers
A team of scientists led by the National Cancer Center Singapore (NCCS) and Duke-NUS Medical School (Duke-NUS) has found a new approach for treating some of the world’s most aggressive cancers associated with BAP1 mutations. Their research, published i…
-
Could one protein play both sides? How Stard7 shifts colon cancer in different models
Alain Chariot’s team has just published a study in EMBO Molecular Medicine shedding light on the unexpected role of the Stard7 protein in the development of intestinal cancers. Long regarded as a simple lipid transporter, Stard7 now emerges as a key pl…
-
A built-in epigenetic clock controls when neurons mature, study suggests
The brain is the most complex organ in the human body. Different parts of the brain perform a variety of functions, all of which are necessary for it to operate in one way or another. These functions are carried out by neurons, which communicate with o…
-
Scalable sensors lower the cost of studying genetic disorders
Researchers have demonstrated a new class of low-cost, scalable sensors that can be used to monitor electrical activity in human cerebral organoids. Because electrical signals are key to understanding brain function, this advancement facilitates resear…
-
Largest genome study of urban Peruvians unlocks clues for precision medicine
Latin American people are represented in fewer than 4% of genetic epidemiological studies around the world. When they are included, they’re often lumped together as one group, despite the rich diversity among different Latin American populations. This …
-
Cause or effect? Study answers question about gene linked with colorectal cancer
A new study has answered a question that has puzzled cancer researchers for decades: Does a genetic defect found in nearly all human colorectal cancers simply accompany the disease, or does it trigger its development? A team led by Harvard Medical Scho…
-
Targeted therapy improves long-term outcomes for patients with rare mutations driving lung cancer
In some non-small cell lung cancers (NSCLCs), changes to the RET gene (known as RET fusions) can drive tumor growth. In a phase 1/2 clinical study with a 42-month-long follow-up period, researchers from Mass General Brigham Cancer Institute recently ev…
-
Genetic overlap between several mental health disorders could help predict vulnerability
Psychiatric disorders, such as bipolar disorder (BD), major depressive disorder (MDD), schizophrenia and anxiety disorders, adversely affect the daily functioning and well-being of millions of people worldwide. Understanding the neural and genetic unde…
-
Probing a paradoxical drug response for irregular heartbeat
Irregular heartbeat, or arrhythmia, can be treated with various procedures or medication, but not all medications work for all patients. In fact, one arrhythmia medication can actually cause arrhythmia in people with a common genetic variant. This prob…
-
Study finds 10-plus genetic markers tied to early follicular lymphoma relapse
Follicular lymphoma (FL) is a type of blood cancer and a form of non-Hodgkin’s lymphoma. Thanks to new treatment breakthroughs, about 80% of FL patients have a survival rate of more than 10 years. The other 20%, however, experience a quickly recurring …
