Categoría: Immunology
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Rare genetic variant protects against malaria-causing parasite by making red blood cells bigger
Scientists have found that a special component in some people’s blood provides them with natural protection against malaria. A recent study has demonstrated that a genetic variant named rs112233623-T reduces the activity of CCND3, a gene that normally …
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New method estimates Epstein-Barr virus in blood using standard genome sequencing data
The Epstein-Barr virus (EBV) can cause certain types of cancer or autoimmune diseases, but how the body controls this common viral infection is largely unknown. Researchers at the University Hospital Bonn (UKB) and the University of Bonn have now ident…
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How age, sex and genetics shape our antibodies
Age, biological sex, and human genetic factors influence the production of antibodies during the immune response. A team of scientists from the Institut Pasteur, the CNRS and the Collège de France have shown that these factors determine not only the qu…
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Gene-editing therapy proves effective for Leber’s hereditary optic neuropathy
A research team has successfully demonstrated the world’s first gene-editing treatment for Leber’s hereditary optic neuropathy (LHON). The study was conducted in collaboration with the Seoul National University College of Veterinary Medicine and Edgene…
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Down syndrome’s unique cancer risk profile mapped across lifespan
Children with Down syndrome have a significantly increased risk of leukemia, while adults have a lower risk of several common solid tumors, according to a new register study from Karolinska Institutet published in the British Journal of Cancer. The res…
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How your life story leaves epigenetic fingerprints on your immune cells
The COVID-19 pandemic gave us tremendous perspective on how wildly symptoms and outcomes can vary between patients experiencing the same infection. How can two people infected by the same pathogen have such different responses? It largely comes down to…
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Immune-targeting vaccine shows promise intercepting cancer in patients with Lynch Syndrome
The investigational cancer vaccine, NOUS-209, was found to safely stimulate the immune system to target precancerous and cancerous cells in individuals with Lynch Syndrome (LS), according to a study from researchers at The University of Texas MD Anders…
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Natural ‘decoy receptor’ protects against inflammatory bowel disease, research reveals
In a study published in Nature Immunology on January 6, a research team led by Prof. Qian Youcun from the Shanghai Institute of Nutrition and Health (SINH) of the Chinese Academy of Sciences identified a new member of the human IL-17 receptor family, I…