Autor: Roman Zug

Why all MODY variants in transcription factor genes are dominantly inherited

Nov 20, 2025

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por

Roman Zug

en Articulos, Enfermedades Raras, Frontiers in Genetics, Opinion

Maturity-onset diabetes of the young (MODY) is an autosomal dominant form of monogenic diabetes, frequently caused by heterozygous loss-of-function variants in transcription factor (TF) genes. Why are MODY variants in TF genes dominantly inherited? Her…