Autor: Houlston, R. S., Dunlop, M. G.
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Colonoscopy surveillance in Lynch syndrome: what it prevents and what it does not
Lynch syndrome (LS), synonymous with hereditary non-polyposis colorectal cancer (HNPCC), is caused by germline pathogenic variants in MLH1, MSH2, MSH6 or PMS2, which confer an elevated lifetime risk of colorectal cancer (CRC). Since the early 2000s, co…