Autor: Guo, R., Wu, H., Zhu, X., Wang, G., Hu, K., Li, K., Geng, H., Xu, C., Zu, C., Gao, Y., Tang, D., Cao, Y., He, X.
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Bi-allelic variants in chromatoid body protein TDRD6 cause spermiogenesis defects and severe oligoasthenoteratozoospermia in humans
BackgroundThe association between the TDRD6 variants and human infertility remains unclear, as only one homozygous missense variant of TDRD6 was found to be associated with oligoasthenoteratozoospermia (OAT).MethodsWhole-exome sequencing and Sanger seq…