Autor: Clinical genetics

In a bid to better understand, and potentially treat, a host of conditions that affect early cognition, neurodevelopment and the brain later in life, investigators at Johns Hopkins Medicine and colleagues throughout the world have been mapping the mole…

Scientists at Sanford Burnham Prebys Medical Discovery Institute and an international team of collaborators have defined a new genetic disease marked by premature aging and deficits in brain function. The researchers have published results in Nature Co…

When a person with cancer finds out they carry an inherited genetic variant that puts them at higher risk of cancer, the results can help inform their treatment or steps to prevent additional cancer.

More than 50 years after Agent Orange was used in Vietnam, a new national study published in Blood Advances highlights the genetic changes that link exposure to Agent Orange to myelodysplastic syndromes (MDS), a group of bone marrow cancers that can pr…

Chinese researchers have developed a novel and highly efficient mitochondrial capsule transplantation therapy, achieving the safe and efficient transplantation of healthy mitochondria into cells and tissues for the first time. This new therapy can sign…

As modern medicine leaps forward in its ability to quickly and more affordably run genetic disease risk tests, ethical questions have swirled about how best to inform people about risk findings they may have had no idea were coming.

A large-scale genetic analysis of East Asian individuals led by Fuu-Jen Tsai of the China Medical University Hospital, finds that people with greater height face a higher risk of endometriosis and atrial fibrillation. A person’s height is the result of…

Adverse childhood experiences and traumatic events experienced or witnessed at any point during one’s lifetime can sometimes prompt the emergence of some mental health disorders, such as post-traumatic stress disorder (PTSD) and complex PTSD (c-PTSD). …

Most of the genetic risk for developing a substance use disorder comes from genes that broadly affect how our brains process rewards, regulate impulses and weigh consequences—not from genes that specifically influence substance use disorder or any sing…

Researchers at Karolinska Institutet have created the first detailed map showing how genetic activity is controlled in individual cells of the adult human brain and spinal cord. The study, published in Nature Neuroscience, shows that oligodendroglia, t…