Return of genome-informed risk-assessment results for common conditions to 23,840 adults and children: An eMERGE network study

The eMERGE Network’s multisite study of nearly 24,000 adults and children demonstrates the feasibility of returning genome-informed risk assessments for 11 diseases. Integrating polygenic risk scores with traditional factors increases high-risk identification. Additional strategies are suggested to improve contact and results return to participants with reported socioeconomic barriers.