Health care impact of comprehensive genomic profiling of solid tumors in patient management using POWER (Precision Oncology at Western University)

Molecular profiling of solid tumors is increasingly essential in oncology practice, guiding diagnosis-prognosis and providing patients with access to molecularly matched therapies that can improve outcomes. In this study, we evaluated 554 patients with advanced solid tumors through the POWER (Precision Oncology at Western University) study, first of its kind Canadian study, designed to prospectively assess clinical impact of expanded Pan-cancer NGS panel testing on patient management, in real-world oncology practice and evaluate the overall health system impact.